: The episode opens with a high-stakes heist at a Vatican City museum . A mysterious villain known as the White Rabbit steals the Force Edge , the legendary sword of the demon knight Sparda.

The first episode of varies significantly depending on whether you are watching the 2025 Netflix adaptation or the 2007 original anime . Netflix Series (2025): " Inferno "

: The White Rabbit’s goal is to tear down the barrier between the human and demon realms, which was originally sealed by Sparda using the Force Edge and a magical amulet. Original Anime (2007): " Devil May Cry "

: It is later revealed that the girl Dante is escorting is a decoy . The real Patty Lowell is an adult woman who used the child to draw out demonic assassins hired by the billionaire's brothers to secure the fortune for themselves.