It refers to a specific genetic variant (NG_009813.1:g.99785T>C) related to Protein S deficiency , a condition that increases the risk of blood clots.
In enthusiast circles, the number is linked to an in-depth history of the Chauchat M1915 , a French machine gun used during World War I. Download 99785 webp
The bacteria don't just mutate; they actually duplicate large segments of their DNA—stretching over hundreds of kilobases—to pump out more of the proteins needed to neutralize the drug. It refers to a specific genetic variant (NG_009813
Published in eLife (article ID 99785), this study highlights how protein balance (proteostasis) limits or allows this "gene dosage" evolution. Military History: The "Chauchat" Machine Gun Published in eLife (article ID 99785), this study
Scientists studied how E. coli bacteria evolve to survive high doses of antibiotics like trimethoprim.
Often called the "worst gun ever," it had a bad habit of jamming due to its open-sided magazine that let in mud and dirt.