Fundamental Concepts For New Clinical Trialists -

Additional data points (e.g., "Does it also improve quality of sleep?").

This is the moral compass of clinical trials. is the genuine uncertainty within the medical community about which treatment is better. If we already know for a fact that Treatment A is superior to Treatment B, it is unethical to start a trial. We only experiment when there is a true "honest doubt" to resolve. Fundamental Concepts for New Clinical Trialists

Blinding (or masking) prevents the "placebo effect" or observer bias from creeping into the data. The patient doesn't know their treatment. Additional data points (e