: Supplemental appendices include normal laboratory values, unit conversion charts, and testing methodology overviews. Critical Interpretative Rules

: Provides information on selecting appropriate specimens (e.g., blood, vitreous humor, bile) and the methodologies used for testing, such as gas chromatography-mass spectrometry (GC-MS).

The handbook covers a broad range of toxicological principles and data essential for determining the cause and manner of death:

: The simple presence of a drug in a reported lethal range does not automatically make it the cause of death if other significant findings (like trauma or natural disease) are present.