The (often referred to simply as the IFM-05 study) focused on using lenalidomide as a maintenance treatment.
Lenalidomide was the primary drug used for maintenance in this study. Key Findings: IFM_05-May 2022
The study demonstrated a clear overall survival benefit for patients receiving maintenance therapy compared to a placebo. The (often referred to simply as the IFM-05
One critical finding was an increased risk of developing a second primary malignancy (SPM) while on long-term lenalidomide maintenance. Patient Considerations One critical finding was an increased risk of
A significant number of patients (roughly 27%) had to stop the maintenance therapy early due to adverse side effects.
Due to the risk of secondary cancers identified in the IFM-05 trial, long-term monitoring for new symptoms or blood changes is standard practice for those on this regimen.
To determine if continuous low-dose chemotherapy after a transplant could improve overall survival and keep the disease controlled for longer periods.