: Billy Crudup (Ashitaka), Claire Danes (San), Minnie Driver (Lady Eboshi), and Gillian Anderson (Moro). 2. Mononoke (2007 TV Series) – Episode 1
If you are looking for the beginning of the legendary Studio Ghibli film, the "first act" introduces the prince Ashitaka and the curse that sets the plot in motion. : Mononoke Hime (Dub) Episode 1
: Prince Ashitaka kills the demon but is inflicted with a deadly curse that manifests as a spreading mark on his arm. : Billy Crudup (Ashitaka), Claire Danes (San), Minnie
If you meant the psychological horror series, Episode 1 begins the first story arc titled . : Billy Crudup (Ashitaka)
: On the advice of the village Oracle, Ashitaka cuts his hair (signifying a permanent departure) and journeys west to find the Forest Spirit and a potential cure.