The story of (known as Saints Row: A harmadik in Hungarian) follows the 3rd Street Saints at the absolute peak of their fame and power . Years after conquering the city of Stilwater, the gang has become a global media empire, complete with their own energy drinks, clothing lines, and action figures. The Fall and the Move to Steelport
: Sophisticated European gangsters led by Loren himself, who control the city's nightlife and vice.
: A Mexican wrestling-themed gang led by the massive Killbane, focused on narcotics and gambling.
The Saints' celebrity status attracts the attention of , a legendary international criminal organization led by Philippe Loren. After a high-stakes bank heist in Stilwater goes wrong, the Saints' leaders—The Boss, Johnny Gat, and Shaundi—are captured. Loren demands they surrender two-thirds of their empire as "tribute". The Saints refuse, leading to a mid-air escape from Loren’s private jet. During the chaos, Johnny Gat is seemingly killed while holding off Syndicate forces to allow the others to escape.
: The Boss chooses to rescue Shaundi and the other Saints from a S.T.A.G. trap. This cement's the Saints' status as the beloved "kings" of Steelport.