C4zip Instant

Aspirating and dispensing the protein sample multiple times to maximize binding.

While C18 is the "gold standard" for peptide mapping, it can bind proteins so tightly that they become nearly impossible to elute. The shorter carbon chain of the C4 resin offers: Aspirating and dispensing the protein sample multiple times

Rinsing with a buffer like 0.1% trifluoroacetic acid (TFA). Allows for desalting and concentrating samples in a

Allows for desalting and concentrating samples in a single, fast step. Standard Workflow for Sample Prep Why C4 over C18

Produced by Millipore , C4 Zip-tips are 10 µL pipette tips containing a specialized C4 (butyl) stationary phase resin. Unlike the more common C18 tips used for peptides, the C4 resin is optimized for larger, more hydrophobic molecules like intact proteins and large polypeptides. Why C4 over C18?

Essential when working with low-abundance samples.